Danny Care (Harlequins) starts at half-back and will become England’s most capped scrum-half (78), moving past 2003 Rugby World Cup winner Matt Dawson.
Following an injury to Ben Youngs (Leicester Tigers), Richard Wigglesworth has been named as a finisher. The 34-year-old Saracens half-back last played for England in 2015.
“The team is hugely excited about playing in front of 82,000 fans at Twickenham and we’ll be well prepared and ready to go out there and beat Wales on Saturday,” said Jones.
Jones added: “Danny Care very much deserves the honour of being the most capped England scrum-half and I am sure he’ll make the most of his opportunity on Saturday.”
England’s pack is unchanged for Saturday’s game, with Dylan Hartley again leading the side. Sam Simmonds, who scored two tries against Italy, starts at number eight.